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Oxidative stress can result from the presence of persistent organic pollutants, metals, pesticides, toxins, pharmaceuticals, and nanomaterials, as well as changes in temperature or oxygen in water, the examined species, with differences in age, sex, or reproductive cycle of an individual

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Their exact function in human hair biology remains under investigation, but the presence of these receptors raises the possibility that GLP-1 medications might directly affect hair follicle cycling, independent of weight loss or nutritional status