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Practitioners may consider AOD 9604 in investigational protocols where IGF-1 elevation is a concern, recognizing that AOD 9604 has no regulatory approval and a narrower, largely preclinical record of efficacy

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These include some heartburn medicines, including esomeprazole (Nexium), famotidine (Pepcid AC), lansoprazole (Prevacid), omeprazole (Prilosec OTC), pantoprazole (Protonix), rabeprazole (Aciphex), as well as some diabetes, gout, and chemotherapy drugs