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The clinical extreme of chronic copper overload is Wilson disease, in which impaired biliary copper excretion produces hepatic and neurological injury a natural experiment demonstrating what happens when the copper regulatory system fails

Revista do Hospital das Clnicas, 59(6), 375-382

The only safe way to temporarily change your eye color is by wearing colored contact lenses that are FDA-approved and prescribed by an optometrist or ophthalmologist

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In 2023 a study conducted jointly at Canadian and Chinese research universities concluded 3 : This study reveals the underlying mechanism of PQQs strong antioxidant capacity and provides evidence for PQQ as a potential agent for clinical prevention and treatment of natural aging-induced osteoporosis