[1] Women using oral contraceptives should use additional contraception for 4 weeks after starting Mounjaro and after each dose increase
A network of doctors treats patients online and prescribes various weight loss medications beyond GLP-1 options
In a phase 2 trial of people who were overweight or had obesity, Boehringer Ingelheims survodutide, which uses both GLP-1 and glucagon, led to weight loss of 19% at 46 weeks
It is believed to work through multiple pathways, including: Blocking voltage-gated sodium channels , reducing neuronal excitability Enhancing GABA (gamma-aminobutyric acid) activity , an inhibitory neurotransmitter Antagonising glutamate receptors , further dampening excitatory neurotransmission Inhibiting carbonic anhydrase enzymes , though the clinical significance of this effect is uncertain While topiramate's primary indications are epilepsy and migraine prophylaxis, it has been observed to cause weight loss as a side effect, likely through appetite suppression and altered taste perception
Early research suggests GLP-1 medications may work differently in cats
