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1,15 Hyperglycemia-induced metabolic pathways Polyol pathway activation In a hyperglycemic state, excess glucose is shunted into the polyol pathway, where aldose reductase catalyzes its reduction to sorbitol, which in turn is oxidized to fructose by sorbitol dehydrogenase

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Sanitize: Swab the combo-vial stopper and the bacteriostatic-water vial with fresh alcohol pads and let them dry