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With the advancement of mechanistic research and the progression of clinical trials, the treatment of CRC is moving toward more personalized and precise approaches, thereby providing patients with more effective and safer treatment options

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In research contexts, investigators typically define model-specific controls, endpoints (for example, scratch-wound assay closure metrics, transwell migration, TEER and barrier-integrity markers, cytokine panels, ECM-related markers), and time points

2012;Suppl 1:001

FDA found no evidence supporting the nominated subcutaneous route