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According to the Summary of Product Characteristics, you should use additional barrier contraceptive methods for 4 weeks after starting treatment and after each dose increase

685 In hypoxic environments, p53 overexpression leads to an increase in glycolytic proteins (GLUT1 and GLUT3) while keeping HK2 levels unchanged, thereby markedly reducing glycolytic flux

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Clinical evidence shows that once-weekly semaglutide provides superior weight-loss effects compared to other GLP-1 receptor agonists in patients with type 2 diabetes