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After FDA approval of enasidenib, a first-in-class drug targeting cancer metabolism via inhibition of IDH2 activity, more studies were conducted with R-2-HG positioned as an oncometabolite

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Gastrointestinal side effects, mostly with symptoms of transient fullness and nausea, are typical for the initiation of treatment

Adjuvant therapy - Infusion of an immunostimulant can improve survival when given with other treatments

In recent years, these experimental compounds have exploded across the worlds of longevity, beauty and fitness, with devotees touting benefits ranging from muscle building and injury recovery to slower aging and improved skin