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Moreover, formulation matters: nanocurcumin produced a substantial antidepressant effect (SMD = 1.30, 95% CI: 2.31 to 0.30), while conventional formulations had negligible impact (SMD = 0.40, 95% CI: 1.04 to 0.24), highlighting the importance of bioavailability-enhanced forms

REDEFINE 1 included 3,417 participants with overweight or obesity but without diabetes (mean age, 47 years

It is studied for its investigated effects on gene expression related to skin regeneration, collagen synthesis, and tissue-repair pathways

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results vary and self-reported outcomes are not independently verified