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De Baere I, Derua R, Janssens V, et al

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The primary pathophysiology of Parkinsons disease is the death of dopaminergic neurons (dopamine-producing cells) and motoneurons in the midbrain (substantia nigra region)

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CHAKRABARTI: And the side effects Judith is describing can also become, as she said, so serious that many people stop taking them, and here's an example of a serious side effect