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In this context, collected data are presented to manifest that sulfonylureas are capable of impacting other ion channels besides K ATP channels, such as TRP and BK Ca , via direct and indirect ways, exhibiting the involvement of diverse ion channels in the modulation of insulin secretion and antidiabetic actions (see Table 1)

Their care model supports clients with nutritional counseling, behavioral guidance, and injectable medication protocols designed to promote appetite regulation, improved glucose control, and gradual fat loss

10.1038/sj.mp.4002089 Mol

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Mild GI symptoms, such as nausea or bloating, may still arise during the adjustment period and often ease over time