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Equivalent Prescriptions, 2019 to 2025 Exhibit 6: State Generic Substitution Policies Exhibit 7: Dispense As Written (DAW) Product Selection Codes Exhibit 8: Top Traditional Therapy Categories, Generic Drugs as a Share of Prescriptions and Purchases, 2024 Exhibit 9: Specialty Prescriptions, Number and Share of Total, 2021 to 2025 Exhibit 10: Factors Determining the Classification of a Specialty Drug, by PBM, 2024 Exhibit 11: Formulary Agreement on Specialty Drug Classification, by PBM, 2023 Exhibit 12: Top Therapy Categories, Share of Non-Discounted Purchases and Average Brand-Name and Generic Prescription Costs, 2025 Exhibit 13: Average Annual Number of Prescriptions per Pharmacy, by Retail Dispensing Format, 2025 Exhibit 14: Average Annual Prescription Revenue per Pharmacy Outlet, by Retail Dispensing Format, 2025 Exhibit 15: Top Four Reasons for Pharmacy Selection, by Dispensing Format Exhibit 16: Pharmacist Work Activities, by Practice Setting, 2022 Exhibit 17: Customer Satisfaction with Pharmacies, by Dispensing Format and Company, 2025 Exhibit 18: Customer Satisfaction with Pharmacies, by Dispensing Format, 2022 vs

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Mechanism literature Multiple peer-reviewed papers describe VEGFR2 activation, eNOS/NO signaling, and tendon-cell behavior in cultured cells and rodent models (Chang et al., Journal of Applied Physiology, 2011

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No regulatory body recommends it