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164 of Lanxi Road, Putuo District, Shanghai, Peoples Republic of China, Email [email protected] Abstract: This review provides a comprehensive examination of the clinical pharmacological mechanisms and broad therapeutic applications of glucagon-like peptide-1 receptor agonists (GLP-1RAs) and dual receptor agonists targeting both glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) receptors

p 24 hours in DIRECT), suggesting that circulating GLP-1 levels probably remain consistently elevated in patients on metformin therapy

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