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10.3390/ijerph15112436 105 Morales-JimnezM.GouveiaL.Yez-FernndezJ.Castro-MuozR.Barragn-HuertaB

BPC-157 modulates the nitric oxide (NO) system via an eNOS / neuronal NOS axis, which according to published observations influences local vasodilation and tissue perfusion

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They also point out that the symptoms that improved in the intervention group were the ones independent of the conventional medications

Some practitioners theorize that establishing robust GLP-1-supporting gut bacteria before discontinuing medication could provide a partial buffer against rebound effects, maintaining some degree of natural GLP-1 production even after the pharmaceutical support is removed