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Activation of the TGF-Smad signaling pathway promotes the differentiation of fibroblasts into myofibroblasts

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The RhoA/ROCK pathway plays a significant role in the differentiation of L-cells and other secretory cells by regulating cytoskeleton dynamics and YAP signaling

Exogenous testosterone can suppress sperm production by shutting down the hypothalamic-pituitary-gonadal axis