excess vitamin C, for instance, is associated with stomach upset and kidney stones
Glutathione is commonly available as: Glutathione supplements come in a variety of forms such as capsules, gels, liquid supplements, skin patches, sprays, and IV injections
Mitochondria and cell death: outer membrane permeabilization and beyond
To achieve GSH depletion in liver, we engineered an adeno-associated virus (AAV) vector encoding Chac1 fused to a Myc tag, driven by the thyroxine-binding globulin (TBG) promoter to achieve liver-specific overexpression of Chac1 (Figure 1B)
After removing and washing away the media, cell proliferation dyelabeled naive CD8 + T cells from OTI mice were cocultured with the BMDMs and tumor cells (Figure 6E)