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Recent advances in Nrf2 activators, such as synthetic triterpenoids and natural compounds, highlight the need for temporal precisionactivating Nrf2 early to preserve -cell function but avoiding chronic overexpression, which may promote cancer (Mohamadi et al., 2023)

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Additionally, the potential for synergistic combination therapies (e.g., ferroptosis inhibitors + tolvaptan or ferroptosis inhibitors + mTOR inhibitors) is understudied

No.: HY-103096CAS No.: 64302-87-0Purity: 99.89%R162 is a potent inhibitor of glutamate dehydrogenase 1 ( GDH1 / GLUD1 ), with anti-cancer properties

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