"Canada is one of many countries experiencing supply challenges
It is studied through vascular marker response, VEGF related signalling, nitric oxide pathway interaction, tendon fibroblast behaviour, collagen matrix organisation and inflammatory marker changes
The most common gastrointestinal side effects include: Nausea very common (may affect more than 1 in 10 people), most pronounced during the first 4-5 weeks Diarrhoea common (may affect up to 1 in 10 people) Vomiting common (may affect up to 1 in 10 people) Abdominal pain common (may affect up to 1 in 10 people) Constipation common (may affect up to 1 in 10 people) Dyspepsia and flatulence common (may affect up to 1 in 10 people) Whilst belching may occur, 'sulphur burps' are not specifically enumerated as a distinct adverse effect in the SmPC
Reliance on monitoring, or retrospective justifications, reflects a fundamental control gap, if not ensured by design
"Unapproved versions do not undergo the FDAs review for safety, effectiveness and quality before they are marketed." The American Diabetes Association's Obesity Association recently published new standards of care that does not recommend the use of non-FDA-approved compounded products