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By extrapolation from the established profiles of approved GLP-1 receptor agonists including semaglutide (Wegovy SmPC, MHRA/EMC) and tirzepatide (Mounjaro SmPC, MHRA/EMC) clinicians should anticipate the need to review and potentially reduce antihypertensive doses as significant weight loss occurs, in line with BNF and NICE guidance principles

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Cree also just wrapped up a clinical trial investigating the use of semaglutide, the active ingredient in Ozempic and Wegovy, for PCOS treatment in adolescent girls

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