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Decreased cystine absorption and increased expression levels of ferroptosis-inhibiting molecules, such as SLC7A11 and GPX4, inhibited the occurrence of ferroptosis in TNBC cells (109)

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Cells synthesize acrolein through various metabolic pathways, including the metabolism of polyamines such as spermine and spermidine by amine oxidase, the breakdown of threonine by neutrophil-derived myeloperoxidase, the breakdown of cancer drugs such as cyclophosphamide, and the lipid peroxidation of polyunsaturated fatty acids (PUFAs) (110, 112)

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