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These exacerbations of dementia symptoms were ameliorated by sustained descent to a lower elevation than his home, as reported in the literature ( This case suggests the bioactivity of the unappreciated component of hyperbaric therapy, barometric pressure, due to the known similar effects in treatment of mountain sickness ( The precedence for our patient's improvement dates back to the 300-year initial history of hyperbaric therapy, which consisted solely of compressed air usage ( The contribution of glutathione (GSH) amino acid precursors to our patient's recovery is impossible to prove but is suggested by the neuroprotective properties of GSH (44)