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In the only published head-to-head skin study, GHK-Cu supported improved collagen in 70% of subjects versus 40% for tretinoin, though tretinoin still leads for surface texture and tone

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Endocrine 88(1):8090 Abi Zeid Daou C, Aboul Hosn O, Ghzayel L, Mourad M (2025) Exploring Connections Between Weight-Loss Medications and Thyroid Cancer: A Look at the FDA Adverse Event Reporting System Database