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Additionally, Arg at the 34th position is replaced with Lys to accommodate site-specific acylation

Serum was analyzed using commercial kits (Biomaghreb Kit) for levels of total cholesterol, triglycerides, LDL cholesterol, and HDL cholesterol according to the protocol described by the manufacturer

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Thus, the mutation most likely will have a deleterious effect on protein function by inducing a state of haploinsufficiency

Glutathione can have a skin-lightening effect because it is known to inhibit the enzyme tyrosinase, which is necessary for the production of melanin (pigment)