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INTRODUCTION Various drugs that cause weight loss are being developed, but many drugs are often eliminated at the stage of obtaining final approval

The best maintenance dose is usually the one you can tolerate and sustain

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Therapeutic Innovation & Regulatory Science, 59(3), 527541

Specifically, we dissect how baseline microbial signatures correlate with differential efficacy, while critically assessing clinical confounding factors, such as metformin co-treatment and dietary shifts, and the methodological limitations that currently hinder the translation of microbiome profiling into precision endocrinology