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The average weight loss in the retatrutide Phase 2 trial was higher than what semaglutide produces in its pivotal trials

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CrossRef Bibliometric analysis of application of radiomics and artificial intelligence integration in personalized treatment of hepatocellular carcinoma Zhujuan Yu, Li Ke, Zhifeng Lin International Journal of Surgery .2026

Semaglutide is a GLP-1 receptor agonist used to treat type 2 diabetes and obesity, with FDA-approved formulations like Ozempic (for diabetes) and Wegovy (for weight loss)

Chronic methylglyoxal infusion by minipump causes pancreatic beta-cell dysfunction and induces type 2 diabetes in Sprague-Dawley rats