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In addition to a decrease in peripheral levels of LAC, LAC levels are decreased by 4060% in the hippocampus and prefrontal cortex of rodents with depressive-like behaviors, including the Flinders Sensitive Line (FSL) rats [30]

2000, 46 (8 Pt 2): 1277-1283

One small study found that a dosage of 1,400 mg 3 times per week for 4 weeks was well tolerated (9)

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Recent FDA communications about compounded GLP-1 medications have created confusion among patients seeking weight loss therapy