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Enhanced Activity of Glutathione Reductase Glutathione reductase is the enzyme responsible for converting oxidized glutathione (GSSG) back to its reduced form (GSH) using NADPH as a cofactor

In addition, in the pathogenesis of GERD, the abnormalities of digestive tract dynamics have gradually been emphasized by researchers, and it has been further found that the brain-gut peptide (neurotransmitter) in the brain-gut axis is not only related to visceral hypersensitivity, but also plays an important role in regulating gastrointestinal dynamics, and changes in the bacterial microbiome and its structure can stimulate the secretion of brain-gut peptide, so the emphasis on the bacterial microbiome in the future research will also provide therapeutic opportunities for the treatment of GERD

Double the starting dose

Kullmann S, Heni M, Fritsche A, Preissl H

Yet some adverse effects are possible at lower doses, although theyre temporary and not life-threatening