In the past, research on the carnitine pool focused mainly on FAO, but it has now expanded to many biological fields, including energy metabolism, mitochondrial homeostasis, epigenetic regulation, inflammatory and immune homeostasis, endocrine regulation, cell signaling, neuroprotection, and tumor biology
Labarrere, [email protected] This article was submitted to Nutritional Immunology, a section of the journal Frontiers in Nutrition Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers
For assessment of glucose-induced insulin secretion, glucose was given orally at a dose of 4 g kg 1 in 6 h fasted mice, followed by blood sampling at timepoints 0, 2, 5, 15 and 30 min after glucose administration
So, if taken in unauthorized quantities, it can also lead to a severe organ system toxicity
Mice were allowed to form the nest, and photographs of nests formed after 12 hours and 24 hours were recorded for scoring analyses later