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The pharmacy benefit manager Prime Therapeutics released a study in October stating that findings indicate in the real world that individuals taking GLP-1 therapies without diabetes [over a two year period] will see no medical cost offset. Analysis of health insurance claims showed that the treatments did not lower other medical costs

We expect all providers of healthcare services, whether NHS or private, and all those with responsibility for prescribing to take appropriate account of national guidance such as National Patient Safety Alerts and Medicine Supply Notifications

Mounjaro typically delivers higher average weight loss in trials (around 20% vs 12 to 15%)

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While the benefits of lipid-lowering therapy may extend beyond reduction of atherosclerotic CV events, given that coronary artery disease is a leading risk factor for HF there is sufficient evidence to warrant strict adherence to existing lipid-lowering therapy guidelines