Very common side effects (affecting more than 1 in 10 people) include: Nausea often the most prominent symptom, usually diminishing over time Diarrhoea may be transient but can occasionally persist Common side effects (affecting up to 1 in 10 people) include: Vomiting Abdominal pain or discomfort Decreased appetite These gastrointestinal symptoms are generally mild to moderate in severity and tend to improve as the body adjusts to the medication
It also lists common adverse reactions such as nausea, diarrhea, decreased appetite, vomiting, constipation, dyspepsia, and abdominal pain
Altogether, when administering GLP-1RA plus SGLT2i combination therapy, it is important to adopt an individualized approach to therapy taking into account individual preferences, costs and coverage, toxicity profile, consideration of kidney function and glucose-lowering efficacy, desire for weight loss, and comorbidities
These physiological responses can accelerate the aging of the skin by breaking down collagen and elastin, leading to the formation of wrinkles and fine lines
If you are still actively losing weight on a GLP-1 drug, your face may continue to change
