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J Vet Intern Med 1987

In early data from a clinical trial, GH deficient patients have increased sleep fragmentation and decreased total sleep time, and it is conjectured that such alterations in sleep patterns may be responsible for excessive daytime sleepiness in such patients (476)

498 Kristensen, P

These include, extreme tiredness, a lack of energy, pins and needles, muscle weakness, disturbed vision, mouth ulcers, a sore and red tongue, and cognitive or psychological concerns such as depression, confusion, and difficulty with memory, understanding or judgement

Clinical evidence shows that GLP-1 activation produces lasting metabolic changes: users maintain weight loss longer after stopping therapy than with older diet drugs, and many experience improved blood pressure and cholesterol without additional medications