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Interestingly, Bex treatment induced APOE and ABCA1 expression in murine brain capillary endothelial cells (mBCEC) in 3xTg AD mice

Nuclear factor E2-related factor 2 (Nrf2), activated by ROS, protects against oxidative stress and chemically induced cell damage

Specifically, the peptide downregulates inflammatory genes including interleukin-1, tumor necrosis factor-, and nuclear factor-B, while upregulating protective genes such as those encoding antioxidant enzymes, DNA repair proteins, and extracellular matrix components

While oral supplements can help, they often dont absorb as effectivelyespecially for those with digestive issues

Dopamine acts on the sympathetic nervous system regulating blood pressure and heart rate (17)