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The decline in folic acid was not owing to bacteria

Following oxidative insult, cellular metabolism is reprogrammed to increase the production of cellular building blocks to replace damaged cellular components

Then, PCBP2 stabilizes Slc7a11, involved in the import of cysteine that is crucial for the synthesis of glutathione and antioxidant responses, preventing bladder cancer cells from ferroptosis [117]

The enzyme glutathione reductase regenerates GSH from GSSG, keeping the antioxidant pool replenished

Therefore, it is not surprising that GSH plays roles in various cellular processes such as cell growth, proliferation, and apoptosis