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As a methoxyindole secreted by the pineal gland, melatonin can increase the number of EPCs and enhance EPCS-mediated angiogenesis by induction HO-1 [132]

These cumulative health advantages may facilitate weight loss and promote general well-being

"The effects of human growth hormone and its lipolytic fragment (AOD9604) on lipid metabolism following chronic treatment in obese mice and beta(3)-AR knock-out mice." Endocrinology 142.12 (2001): 5182-5189

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Besides exercise and nutrition, the paper also highlights weight loss, caloric restriction, and metabolic flexibility as key strategies to reduce oxidative load and improve glutathione recycling