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(31) The time at which someone starts a treatment for obesity can itself be correlated with mental health difficulties, and the effects of the medication on weight, whether this is a dramatic reduction in weight, or a disappointing lack of weight reduction, can also trigger changes in mental health. (32) Based on major long-term trials, including FLOW (chronic kidney disease), SELECT (obesity/cardiovascular disease without diabetes), and SUSTAIN-6 (type 2 diabetes), semaglutide has demonstrated significant benefits across the cardiovascular and renal systems

Factors include your weight, age, kidney and liver function, other medications you take, and your overall health condition

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Louwagie, MD, PhD, of the Department of Internal Medicine at LewisGale Hospital Montgomery in Blacksburg, Va

Drugs like retatrutide, CagriSema, survodutide, and orforglipron are designed to build on what Ozempic started