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Studies on anticancer activities of antimicrobial peptides

Although the aforementioned studies have demonstrated that targeting the necroptosis pathway is a viable strategy in AML, the clinical relevance of the RIPK1/RIPK3/MLKL axis remains unclear (135137)

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In this study, a dual stimuli-responsive prodrug nanosystem (MSNs-ss-SA) was synthesized by conjugating SA to functionalized disulfide-doped mesoporous silica nanoparticles (MSNs-ss-NH 2 ) via amide bonds to facilitate the efficient delivery of SA and bioavailable silicon concurrently

Older individuals show heightened mitochondrial senescence, significantly contributing to various aging-related disease mechanisms [150]