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This point could be elucidated by the lack of response to B12 treatment in congenital methylmalonic aciduria resultant from MMUT gene mutations

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These findings underscore oral microbes as upstream regulators of the gutbrain axis and provide a microbialneural perspective on the pathological link between periodontitis and depression (Figure 2)

For individuals looking for natural alternatives to diabetes medication like GLP-1 agonists, boosting protein intake could improve GLP-1 response

139 Thus, the effects of any DR regime are exacerbated in mice, explaining why DR as a monotherapy has worked in preclinical studies but not in humans