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J Med Chem (2007) 50:612632

Nausea is common after starting these medications, but this generally ameliorates after 1-2 weeks of therapy

p = 0.001] and lumbar spine BMD [ETD: 0.018 g/cm 3 (95% CI: 0.031 to 0.005)

Notably, while leptin did not alter GH secretion in normally fed rats, it reversed the inhibitory effects of fasting on GH secretion and enhanced responses to GHRH and GHRP-6 in fasted rats [36,37,38]

Given that the PVN is a crucial brain region for sensing stress 51,52 , these findings could also explain that acute stress and chronic negative mood disorders cause disturbances in intestinal functions 53 , such as diarrhea and constipation 54,55