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(29, 30) In a follow-up study by the same researchers, four groups were created from the initial 71 patients who agreed to participate in the first study

Under physiological conditions, ascorbic acid is ionized to ascorbate anion, which, after entering the digestive tract as a nutrient, is absorbed from the lumen of the intestinemainly by enterocytesand circulates with the blood throughout the body, so it can be taken up by all cells [12]

Then, QCT could suppress the Erastin-induced elevation in the phosphorylated AKT (pAKT) to AKT ratio and attenuated the reduction in GPX4 expression, which was not exerted by QCT after down-regulation of EGFR