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Body Weight Change After 14 Weeks of Setmelanotide Treatment Compared to Placebo In the placebo-controlled analysis of pivotal patients aged greater than or equal to 12 years with BBS, patients receiving setmelanotide (N = 14) had a greater mean percentage body weight change (3.31%

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The complete coding algorithms used for identifying patient characteristics, clinical diagnoses, medical procedures, pharmaceutical prescriptions, and laboratory parameters are detailed in Supplementary Table 1