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Di Chiacchio N, Jasso-Olivares JC, Di Chiacchio NG, Jacinto JA, Restrepo MV

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The primary regulator of mitophagy is the PTEN-induced putative kinase protein-1 (PINK1)/Parkin pathway, although the FUN14 domain-containing 1 (FUNDC1), Bcl2-interacting protein 3 (BNIP3) and BNIP3-like (BNIP3L/NIX) pathways can also control mitophagy