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Recurrent isolated neonatal hemolytic anemia: think about glutathione synthetase deficiency

AHAs/BHAs: Acidic environments may reduce peptide activity

Apart from the low propensity of the GSAAT(C168S) and GSAAT(C190S) mutants to dimerize, these single substitution mutants not only failed to promote redox-dependent dimerization and oxidation of monomeric GSAAT, but even prevented it

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Overnight changes are highly unlikely, but regular use can increase collagen production, reduce dark spots, and strengthen the skin barrier