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Repaglinide (Prandin), a benzoic acid derivative introduced in 1998, was the first member of the meglitinide class

By activating GLP-1 receptors, Semaglutide enhances insulin secretion in response to meals, suppresses glucagon release (a hormone that raises blood sugar levels), and slows gastric emptying

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It is the kind of complementary strategy that longevity researchers increasingly point to as a more complete way of supporting the metabolic pathways associated with healthspan