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The antioxidant effect was demonstrated by improvements in parameters such as MDA, CAT and GSH levels and increased levels of the SOD enzyme (135,141)

By contrast, antioxidant shielding refers to a deliberately restricted protection of non-malignant tissues from therapy-associated oxidative damage without restoring redox fitness in tumor cells

Eisalou MY, Farahpour MR

The following occurred in the respective cases: sodium and chloride depletion fluid overload septicemia, or blood poisoning, in an individual with existing compromised liver function and portal hypertension While underlying conditions may have increased the risk of severe side effects or death in some cases, these findings suggest that coffee enemas are generally not safe

Sheng R, Zhang Y, Sun W, Ji Y, Zeng M, Yao X, Dai Y