This table compares the active ingredients, FDA-approved usage, and typical weight loss or A1C reduction of some of the most well-known GLP-1s: Semaglutide vs tirzepatide Semaglutide is the active ingredient found in the injectable medications Ozempic and Wegovy (and the oral medication Rybelsus)
A properly stored lyophilized semaglutide vial contains a single white-to-off-white cake or powder at the bottom
Medications for weight management used without these cornerstones will only provide a temporary change and not be effective long term
However, for prescription use or long-term treatment, consult your doctor before stopping as sudden discontinuation may cause rebound acid production, making symptoms worse than before treatment
To get the full dose, inject semaglutide at a 90-degree angle, keep the needle in place for the recommended time, and always use a new, sterile needle to avoid contamination and blockage