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Interestingly, increase in circulating LIGHT together with hepatic increase of its two membrane-bound receptors, HVEM and lymphotoxin receptor (LTR), were shown in patients with NAFLD compared to controls [52]
Surrogate Cardiometabolic Endpoints RCTs consistently demonstrate that combined SGLT2i and GLP-1RA therapy provides benefits in glycemic control, body weight, and blood pressure compared with either medication alone
A comprehensive cardiovascular assessment should form part of the pre-treatment evaluation
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