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TB-500 has been studied for its role in: Actin polymerisation and regulation of cell migration

FOXO4-DRI improves the testicular microenvironment in naturally aged mice FOXO4-DRI-treated aged testes showed decreased interstitial SA--gal activity (Figure 7A) as well as lower levels of senescence-associated proteins p53, p21, and p16 (Figure 7B7E)

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