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This relationship was also observed in the IPTW cohort via weighted Cox proportional hazards models showing a decreased risk for asthma attacks with metformin (HR = 0.76

SYNCHRONIZE-CVOT is an event driven cardiovascular outcome trial enrolling patients with preobesity or obesity with cardiovascular disease, chronic kidney disease, or risk factors for cardiovascular disease

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TAG is a glycerol attached to mixture of saturated and unsaturated fatty acids (Fig