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Patients should be counseled to maintain adequate fluid intake and monitor for signs of dehydration, including dark urine, dizziness, or decreased urination, which warrant medical evaluation

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p = 0.048), while once weekly semaglutide was preferentially added to a treatment regimen with metformin and basal insulin than oral semaglutide (9% versus 1.75%

Furthermore, there is a lack of randomized controlled trials, standardized outcome measures, and long-term follow-up reports