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Experimental autoimmune thyroiditis (EAT) models have demonstrated that pharmacological blockade of S1P signaling ameliorates thyroid inflammation and reduces TSH levels, underscoring a bidirectional crosstalk between thyroid dysfunction and liver inflammation via ECM pathways (93)

Liver and visceral fat also decreased significantly [4]

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Cytokine Measurement Levels of IL-2, IL-6, IL-12, IL-17, IL-10, IFN-, TGF-1, and TNF- were measured in the lung tissue homogenates from untreated, 40 mM L-GSH, RIF, and RIF +40 mM L-GSH treated mice using enzyme-linked immunosorbent assay (ELISA) kits: IL-12 p70 Mouse Uncoated ELISA Kit (Cat # 887,12188), IL-6 Mouse Uncoated ELISA Kit (Cat # 887,06488), IL-2 Mouse Uncoated ELISA Kit (Cat #887,02488), IL-17A (homodimer) Mouse Uncoated ELISA Kit (Cat # 887,37186), IL-10 Mouse Uncoated ELISA Kit (Cat